Barry H. Honig is an American biochemist, molecular and computational biophysicist born in 1941. He is currently a professor at the Columbia University Vagelos College of Physicians and Surgeons, where he teaches in the Departments of Systems Biology, Biochemistry and Molecular Biophysics, and Medicine. Honig is also a member of the Zuckerman Mind, Brain Behavior Institute and has been an investigator for the Howard Hughes Medical Institute (HHMI) from 2000 to 2019.
Honig received his B.Sc. summa cum laude in chemistry from the Polytechnic Institute of Brooklyn in 1963 and a M.Sc. from Johns Hopkins University in 1964. He then obtained his Ph.D. in chemical physics from the Weizmann Institute in 1968, under the supervision of Joshua Jortner.
From 1968 to 1970, Honig was a postdoc at Harvard University under Martin Karplus, and from 1970 to 1973, he continued his postdoc at Columbia University with Cyrus Levinthal. He then held associate professor positions at the Hebrew University in Jerusalem from 1973 to 1979 and at the University of Illinois Urbana-Champaign from 1979 to 1981.
Honig's research focuses on understanding the fundamental physical principles that govern the behavior of molecules, particularly in the context of neuronal development. He combines biology, chemistry, and physics to study sticky molecules called cadherins and protocadherins that play a crucial role in cell recognition and brain development. These molecules are also key to understanding brain diseases such as epilepsy and autism.
Honig is known for innovating methods to compute and visualize the electrostatic potentials of macromolecules based on their 3D structures. He developed the widely used computer programs DelPhi and GRASP in his laboratory.
Honig has also made significant contributions to the understanding of the spectroscopic and photochemical properties of visual pigments, the computational prediction of protein structure and function, and the structural basis of protein-DNA interactions.
Honig is a member of prestigious organizations such as the National Academy of Sciences, the American Academy of Arts and Sciences, and the American Association for Advancement of Science. He has received numerous awards, including:
He is also an elected fellow of the International Society of Computational Biology (ISCB) and the Biophysical Society.
Barry Honig Columbia University http://honig.c2b2.columbia.edu/ Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons A Nicholls, KA Sharp, B Honig Proteins: Structure, Function, and Bioinformatics 11 (4), 281-296, 1991 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:eGYfIraVYiQC Cited by: 6465
Classical electrostatics in biology and chemistry B Honig, A Nicholls Science 268 (5214), 1144-1149, 1995 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:70eg2SAEIzsC Cited by: 3523
Accurate calculation of hydration free energies using macroscopic solvent models D Sitkoff, KA Sharp, B Honig The Journal of Physical Chemistry 98 (7), 1978-1988, 1994 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:XoXfffV-tXoC Cited by: 2481
A hierarchical approach to all‐atom protein loop prediction MP Jacobson, DL Pincus, CS Rapp, TJF Day, B Honig, DE Shaw, … Proteins: Structure, Function, and Bioinformatics 55 (2), 351-367, 2004 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:SnGPuo6Feq8C Cited by: 2291
Interactions in macromolecules: theory and applications KA Sharp, B Honi Annu. Rev. Biophys. Biophys. Chem 19 (301), 32, 1990 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:uDGL6kOW6j0C Cited by: 1702
The Wilson Disease Gene is a Copper Transporting ATPase with Homology to the Menkes' Disease Gene
. Nature Genetics 5, 344-350, 1993 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:LK8CI43ZvvMC Cited by: 1688
A rapid finite difference algorithm, utilizing successive over‐relaxation to solve the Poisson–Boltzmann equation A Nicholls, B Honig Journal of computational chemistry 12 (4), 435-445, 1991 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:7Hz3ACDFbsoC Cited by: 1567
Calculating the electrostatic potential of molecules in solution: method and error assessment MK Gilson, KA Sharp, BH Honig Journal of computational chemistry 9 (4), 327-335, 1988 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:mlAyqtXpCwEC Cited by: 1416
On the role of the crystal environment in determining protein side-chain conformations MP Jacobson, RA Friesner, Z Xiang, B Honig Journal of molecular biology 320 (3), 597-608, 2002 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:3fE2CSJIrl8C Cited by: 1253
Accurate first principles calculation of molecular charge distributions and solvation energies from ab initio quantum mechanics and continuum dielectric theory DJ Tannor, B Marten, R Murphy, RA Friesner, D Sitkoff, A Nicholls, … Journal of the American Chemical Society 116 (26), 11875-11882, 1994 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:vDZJ-YLwNdEC Cited by: 1223
The role of DNA shape in protein–DNA recognition R Rohs, SM West, A Sosinsky, P Liu, RS Mann, B Honig Nature 461 (7268), 1248-1253, 2009 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:kcbZDykSQC Cited by: 1173
GRASP: graphical representation and analysis of surface properties A Nicholls, R Bharadwaj, B Honig Biophys. J 64 (2), A166-A166, 1993 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:mel-f30kHHgC Cited by: 1130
New model for calculation of solvation free energies: correction of self-consistent reaction field continuum dielectric theory for short-range hydrogen-bonding effects B Marten, K Kim, C Cortis, RA Friesner, RB Murphy, MN Ringnalda, … The Journal of Physical Chemistry 100 (28), 11775-11788, 1996 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:L1USKYWJimsC Cited by: 1116
Origins of specificity in protein-DNA recognition R Rohs, X Jin, SM West, R Joshi, B Honig, RS Mann Annual review of biochemistry 79 (1), 233-269, 2010 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:ziOE8S1-AIUC Cited by: 1043
Calculation of the total electrostatic energy of a macromolecular system: solvation energies, binding energies, and conformational analysis MK Gilson, B Honig Proteins: Structure, Function, and Bioinformatics 4 (1), 7-18, 1988 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:e5wmG9Sq2KIC Cited by: 1038
Extending the applicability of the nonlinear Poisson− Boltzmann equation: multiple dielectric constants and multivalent ions W Rocchia, E Alexov, B Honig The Journal of Physical Chemistry B 105 (28), 6507-6514, 2001 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:YsMSGLbcyi4C Cited by: 997
Focusing of electric fields in the active site of Cu‐Zn superoxide dismutase: Effects of ionic strength and amino‐acid modification I Klapper, R Hagstrom, R Fine, K Sharp, B Honig Proteins: Structure, Function, and Bioinformatics 1 (1), 47-59, 1986 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:RJOyoaXV5v8C Cited by: 976
Electrostatic aspects of protein–protein interactions FB Sheinerman, R Norel, B Honig Current opinion in structural biology 10 (2), 153-159, 2000 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:mWEH9CqjF64C Cited by: 975
Structure-based prediction of protein–protein interactions on a genome-wide scale QC Zhang, D Petrey, L Deng, L Qiang, Y Shi, CA Thu, B Bisikirska, … Nature 490 (7421), 556-560, 2012 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:j7_hQOaDUrUC Cited by: 772
Reevaluation of the Born model of ion hydration AA Rashin, B Honig The journal of physical chemistry 89 (26), 5588-5593, 1985 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:mB3voiENLucC Cited by: 739
Barry Honig Columbia University http://honig.c2b2.columbia.edu/ Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons A Nicholls, KA Sharp, B Honig Proteins: Structure, Function, and Bioinformatics 11 (4), 281-296, 1991 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:eGYfIraVYiQC Cited by: 6465
Classical electrostatics in biology and chemistry B Honig, A Nicholls Science 268 (5214), 1144-1149, 1995 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:70eg2SAEIzsC Cited by: 3523
Accurate calculation of hydration free energies using macroscopic solvent models D Sitkoff, KA Sharp, B Honig The Journal of Physical Chemistry 98 (7), 1978-1988, 1994 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:XoXfffV-tXoC Cited by: 2481
A hierarchical approach to all‐atom protein loop prediction MP Jacobson, DL Pincus, CS Rapp, TJF Day, B Honig, DE Shaw, … Proteins: Structure, Function, and Bioinformatics 55 (2), 351-367, 2004 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:SnGPuo6Feq8C Cited by: 2291
Interactions in macromolecules: theory and applications KA Sharp, B Honi Annu. Rev. Biophys. Biophys. Chem 19 (301), 32, 1990 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:uDGL6kOW6j0C Cited by: 1702
The Wilson Disease Gene is a Copper Transporting ATPase with Homology to the Menkes' Disease Gene
. Nature Genetics 5, 344-350, 1993 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:LK8CI43ZvvMC Cited by: 1688
A rapid finite difference algorithm, utilizing successive over‐relaxation to solve the Poisson–Boltzmann equation A Nicholls, B Honig Journal of computational chemistry 12 (4), 435-445, 1991 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:7Hz3ACDFbsoC Cited by: 1567
Calculating the electrostatic potential of molecules in solution: method and error assessment MK Gilson, KA Sharp, BH Honig Journal of computational chemistry 9 (4), 327-335, 1988 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:mlAyqtXpCwEC Cited by: 1416
On the role of the crystal environment in determining protein side-chain conformations MP Jacobson, RA Friesner, Z Xiang, B Honig Journal of molecular biology 320 (3), 597-608, 2002 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:3fE2CSJIrl8C Cited by: 1253
Accurate first principles calculation of molecular charge distributions and solvation energies from ab initio quantum mechanics and continuum dielectric theory DJ Tannor, B Marten, R Murphy, RA Friesner, D Sitkoff, A Nicholls, … Journal of the American Chemical Society 116 (26), 11875-11882, 1994 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:vDZJ-YLwNdEC Cited by: 1223
The role of DNA shape in protein–DNA recognition R Rohs, SM West, A Sosinsky, P Liu, RS Mann, B Honig Nature 461 (7268), 1248-1253, 2009 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:kcbZDykSQC Cited by: 1173
GRASP: graphical representation and analysis of surface properties A Nicholls, R Bharadwaj, B Honig Biophys. J 64 (2), A166-A166, 1993 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:mel-f30kHHgC Cited by: 1130
New model for calculation of solvation free energies: correction of self-consistent reaction field continuum dielectric theory for short-range hydrogen-bonding effects B Marten, K Kim, C Cortis, RA Friesner, RB Murphy, MN Ringnalda, … The Journal of Physical Chemistry 100 (28), 11775-11788, 1996 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:L1USKYWJimsC Cited by: 1116
Origins of specificity in protein-DNA recognition R Rohs, X Jin, SM West, R Joshi, B Honig, RS Mann Annual review of biochemistry 79 (1), 233-269, 2010 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:ziOE8S1-AIUC Cited by: 1043
Calculation of the total electrostatic energy of a macromolecular system: solvation energies, binding energies, and conformational analysis MK Gilson, B Honig Proteins: Structure, Function, and Bioinformatics 4 (1), 7-18, 1988 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:e5wmG9Sq2KIC Cited by: 1038
Extending the applicability of the nonlinear Poisson− Boltzmann equation: multiple dielectric constants and multivalent ions W Rocchia, E Alexov, B Honig The Journal of Physical Chemistry B 105 (28), 6507-6514, 2001 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:YsMSGLbcyi4C Cited by: 997
Focusing of electric fields in the active site of Cu‐Zn superoxide dismutase: Effects of ionic strength and amino‐acid modification I Klapper, R Hagstrom, R Fine, K Sharp, B Honig Proteins: Structure, Function, and Bioinformatics 1 (1), 47-59, 1986 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:RJOyoaXV5v8C Cited by: 976
Electrostatic aspects of protein–protein interactions FB Sheinerman, R Norel, B Honig Current opinion in structural biology 10 (2), 153-159, 2000 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:mWEH9CqjF64C Cited by: 975
Structure-based prediction of protein–protein interactions on a genome-wide scale QC Zhang, D Petrey, L Deng, L Qiang, Y Shi, CA Thu, B Bisikirska, … Nature 490 (7421), 556-560, 2012 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:j7_hQOaDUrUC Cited by: 772
Reevaluation of the Born model of ion hydration AA Rashin, B Honig The journal of physical chemistry 89 (26), 5588-5593, 1985 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:mB3voiENLucC Cited by: 739
Barry Honig Columbia University http://honig.c2b2.columbia.edu/ Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons A Nicholls, KA Sharp, B Honig Proteins: Structure, Function, and Bioinformatics 11 (4), 281-296, 1991 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:eGYfIraVYiQC Cited by: 6465
Classical electrostatics in biology and chemistry B Honig, A Nicholls Science 268 (5214), 1144-1149, 1995 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:70eg2SAEIzsC Cited by: 3523
Accurate calculation of hydration free energies using macroscopic solvent models D Sitkoff, KA Sharp, B Honig The Journal of Physical Chemistry 98 (7), 1978-1988, 1994 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:XoXfffV-tXoC Cited by: 2481
A hierarchical approach to all‐atom protein loop prediction MP Jacobson, DL Pincus, CS Rapp, TJF Day, B Honig, DE Shaw, … Proteins: Structure, Function, and Bioinformatics 55 (2), 351-367, 2004 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:SnGPuo6Feq8C Cited by: 2291
Interactions in macromolecules: theory and applications KA Sharp, B Honi Annu. Rev. Biophys. Biophys. Chem 19 (301), 32, 1990 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:uDGL6kOW6j0C Cited by: 1702
The Wilson Disease Gene is a Copper Transporting ATPase with Homology to the Menkes' Disease Gene
. Nature Genetics 5, 344-350, 1993 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:LK8CI43ZvvMC Cited by: 1688
A rapid finite difference algorithm, utilizing successive over‐relaxation to solve the Poisson–Boltzmann equation A Nicholls, B Honig Journal of computational chemistry 12 (4), 435-445, 1991 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:7Hz3ACDFbsoC Cited by: 1567
Calculating the electrostatic potential of molecules in solution: method and error assessment MK Gilson, KA Sharp, BH Honig Journal of computational chemistry 9 (4), 327-335, 1988 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:mlAyqtXpCwEC Cited by: 1416
On the role of the crystal environment in determining protein side-chain conformations MP Jacobson, RA Friesner, Z Xiang, B Honig Journal of molecular biology 320 (3), 597-608, 2002 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:3fE2CSJIrl8C Cited by: 1253
Accurate first principles calculation of molecular charge distributions and solvation energies from ab initio quantum mechanics and continuum dielectric theory DJ Tannor, B Marten, R Murphy, RA Friesner, D Sitkoff, A Nicholls, … Journal of the American Chemical Society 116 (26), 11875-11882, 1994 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:vDZJ-YLwNdEC Cited by: 1223
The role of DNA shape in protein–DNA recognition R Rohs, SM West, A Sosinsky, P Liu, RS Mann, B Honig Nature 461 (7268), 1248-1253, 2009 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:kcbZDykSQC Cited by: 1173
GRASP: graphical representation and analysis of surface properties A Nicholls, R Bharadwaj, B Honig Biophys. J 64 (2), A166-A166, 1993 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:mel-f30kHHgC Cited by: 1130
New model for calculation of solvation free energies: correction of self-consistent reaction field continuum dielectric theory for short-range hydrogen-bonding effects B Marten, K Kim, C Cortis, RA Friesner, RB Murphy, MN Ringnalda, … The Journal of Physical Chemistry 100 (28), 11775-11788, 1996 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:L1USKYWJimsC Cited by: 1116
Origins of specificity in protein-DNA recognition R Rohs, X Jin, SM West, R Joshi, B Honig, RS Mann Annual review of biochemistry 79 (1), 233-269, 2010 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:ziOE8S1-AIUC Cited by: 1043
Calculation of the total electrostatic energy of a macromolecular system: solvation energies, binding energies, and conformational analysis MK Gilson, B Honig Proteins: Structure, Function, and Bioinformatics 4 (1), 7-18, 1988 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:e5wmG9Sq2KIC Cited by: 1038
Extending the applicability of the nonlinear Poisson− Boltzmann equation: multiple dielectric constants and multivalent ions W Rocchia, E Alexov, B Honig The Journal of Physical Chemistry B 105 (28), 6507-6514, 2001 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:YsMSGLbcyi4C Cited by: 997
Focusing of electric fields in the active site of Cu‐Zn superoxide dismutase: Effects of ionic strength and amino‐acid modification I Klapper, R Hagstrom, R Fine, K Sharp, B Honig Proteins: Structure, Function, and Bioinformatics 1 (1), 47-59, 1986 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:RJOyoaXV5v8C Cited by: 976
Electrostatic aspects of protein–protein interactions FB Sheinerman, R Norel, B Honig Current opinion in structural biology 10 (2), 153-159, 2000 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:mWEH9CqjF64C Cited by: 975
Structure-based prediction of protein–protein interactions on a genome-wide scale QC Zhang, D Petrey, L Deng, L Qiang, Y Shi, CA Thu, B Bisikirska, … Nature 490 (7421), 556-560, 2012 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:j7_hQOaDUrUC Cited by: 772
Reevaluation of the Born model of ion hydration AA Rashin, B Honig The journal of physical chemistry 89 (26), 5588-5593, 1985 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:mB3voiENLucC Cited by: 739
Barry Honig Columbia University http://honig.c2b2.columbia.edu/ Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons A Nicholls, KA Sharp, B Honig Proteins: Structure, Function, and Bioinformatics 11 (4), 281-296, 1991 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:eGYfIraVYiQC Cited by: 6465
Classical electrostatics in biology and chemistry B Honig, A Nicholls Science 268 (5214), 1144-1149, 1995 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:70eg2SAEIzsC Cited by: 3523
Accurate calculation of hydration free energies using macroscopic solvent models D Sitkoff, KA Sharp, B Honig The Journal of Physical Chemistry 98 (7), 1978-1988, 1994 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:XoXfffV-tXoC Cited by: 2481
A hierarchical approach to all‐atom protein loop prediction MP Jacobson, DL Pincus, CS Rapp, TJF Day, B Honig, DE Shaw, … Proteins: Structure, Function, and Bioinformatics 55 (2), 351-367, 2004 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:SnGPuo6Feq8C Cited by: 2291
Interactions in macromolecules: theory and applications KA Sharp, B Honi Annu. Rev. Biophys. Biophys. Chem 19 (301), 32, 1990 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:uDGL6kOW6j0C Cited by: 1702
The Wilson Disease Gene is a Copper Transporting ATPase with Homology to the Menkes' Disease Gene
. Nature Genetics 5, 344-350, 1993 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:LK8CI43ZvvMC Cited by: 1688
A rapid finite difference algorithm, utilizing successive over‐relaxation to solve the Poisson–Boltzmann equation A Nicholls, B Honig Journal of computational chemistry 12 (4), 435-445, 1991 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:7Hz3ACDFbsoC Cited by: 1567
Calculating the electrostatic potential of molecules in solution: method and error assessment MK Gilson, KA Sharp, BH Honig Journal of computational chemistry 9 (4), 327-335, 1988 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:mlAyqtXpCwEC Cited by: 1416
On the role of the crystal environment in determining protein side-chain conformations MP Jacobson, RA Friesner, Z Xiang, B Honig Journal of molecular biology 320 (3), 597-608, 2002 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:3fE2CSJIrl8C Cited by: 1253
Accurate first principles calculation of molecular charge distributions and solvation energies from ab initio quantum mechanics and continuum dielectric theory DJ Tannor, B Marten, R Murphy, RA Friesner, D Sitkoff, A Nicholls, … Journal of the American Chemical Society 116 (26), 11875-11882, 1994 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:vDZJ-YLwNdEC Cited by: 1223
The role of DNA shape in protein–DNA recognition R Rohs, SM West, A Sosinsky, P Liu, RS Mann, B Honig Nature 461 (7268), 1248-1253, 2009 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:kcbZDykSQC Cited by: 1173
GRASP: graphical representation and analysis of surface properties A Nicholls, R Bharadwaj, B Honig Biophys. J 64 (2), A166-A166, 1993 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:mel-f30kHHgC Cited by: 1130
New model for calculation of solvation free energies: correction of self-consistent reaction field continuum dielectric theory for short-range hydrogen-bonding effects B Marten, K Kim, C Cortis, RA Friesner, RB Murphy, MN Ringnalda, … The Journal of Physical Chemistry 100 (28), 11775-11788, 1996 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:L1USKYWJimsC Cited by: 1116
Origins of specificity in protein-DNA recognition R Rohs, X Jin, SM West, R Joshi, B Honig, RS Mann Annual review of biochemistry 79 (1), 233-269, 2010 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:ziOE8S1-AIUC Cited by: 1043
Calculation of the total electrostatic energy of a macromolecular system: solvation energies, binding energies, and conformational analysis MK Gilson, B Honig Proteins: Structure, Function, and Bioinformatics 4 (1), 7-18, 1988 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:e5wmG9Sq2KIC Cited by: 1038
Extending the applicability of the nonlinear Poisson− Boltzmann equation: multiple dielectric constants and multivalent ions W Rocchia, E Alexov, B Honig The Journal of Physical Chemistry B 105 (28), 6507-6514, 2001 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:YsMSGLbcyi4C Cited by: 997
Focusing of electric fields in the active site of Cu‐Zn superoxide dismutase: Effects of ionic strength and amino‐acid modification I Klapper, R Hagstrom, R Fine, K Sharp, B Honig Proteins: Structure, Function, and Bioinformatics 1 (1), 47-59, 1986 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:RJOyoaXV5v8C Cited by: 976
Electrostatic aspects of protein–protein interactions FB Sheinerman, R Norel, B Honig Current opinion in structural biology 10 (2), 153-159, 2000 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:mWEH9CqjF64C Cited by: 975
Structure-based prediction of protein–protein interactions on a genome-wide scale QC Zhang, D Petrey, L Deng, L Qiang, Y Shi, CA Thu, B Bisikirska, … Nature 490 (7421), 556-560, 2012 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:j7_hQOaDUrUC Cited by: 772
Reevaluation of the Born model of ion hydration AA Rashin, B Honig The journal of physical chemistry 89 (26), 5588-5593, 1985 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:mB3voiENLucC Cited by: 739
Barry Honig
Columbia University
http://honig.c2b2.columbia.edu/
Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons A Nicholls, KA Sharp, B Honig Proteins: Structure, Function, and Bioinformatics 11 (4), 281-296, 1991 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:eGYfIraVYiQC Cited by: 6465
Classical electrostatics in biology and chemistry B Honig, A Nicholls Science 268 (5214), 1144-1149, 1995 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:70eg2SAEIzsC Cited by: 3524
Accurate calculation of hydration free energies using macroscopic solvent models D Sitkoff, KA Sharp, B Honig The Journal of Physical Chemistry 98 (7), 1978-1988, 1994 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:XoXfffV-tXoC Cited by: 2481
A hierarchical approach to all‐atom protein loop prediction MP Jacobson, DL Pincus, CS Rapp, TJF Day, B Honig, DE Shaw, … Proteins: Structure, Function, and Bioinformatics 55 (2), 351-367, 2004 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:SnGPuo6Feq8C Cited by: 2291
Interactions in macromolecules: theory and applications KA Sharp, B Honi Annu. Rev. Biophys. Biophys. Chem 19 (301), 32, 1990 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:uDGL6kOW6j0C Cited by: 1702
The Wilson Disease Gene is a Copper Transporting ATPase with Homology to the Menkes' Disease Gene
. Nature Genetics 5, 344-350, 1993 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:LK8CI43ZvvMC Cited by: 1688
A rapid finite difference algorithm, utilizing successive over‐relaxation to solve the Poisson–Boltzmann equation A Nicholls, B Honig Journal of computational chemistry 12 (4), 435-445, 1991 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:7Hz3ACDFbsoC Cited by: 1567
Calculating the electrostatic potential of molecules in solution: method and error assessment MK Gilson, KA Sharp, BH Honig Journal of computational chemistry 9 (4), 327-335, 1988 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:mlAyqtXpCwEC Cited by: 1416
On the role of the crystal environment in determining protein side-chain conformations MP Jacobson, RA Friesner, Z Xiang, B Honig Journal of molecular biology 320 (3), 597-608, 2002 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:3fE2CSJIrl8C Cited by: 1253
Accurate first principles calculation of molecular charge distributions and solvation energies from ab initio quantum mechanics and continuum dielectric theory DJ Tannor, B Marten, R Murphy, RA Friesner, D Sitkoff, A Nicholls, … Journal of the American Chemical Society 116 (26), 11875-11882, 1994 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:vDZJ-YLwNdEC Cited by: 1223
The role of DNA shape in protein–DNA recognition R Rohs, SM West, A Sosinsky, P Liu, RS Mann, B Honig Nature 461 (7268), 1248-1253, 2009 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:kcbZDykSQC Cited by: 1173
GRASP: graphical representation and analysis of surface properties A Nicholls, R Bharadwaj, B Honig Biophys. J 64 (2), A166-A166, 1993 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:mel-f30kHHgC Cited by: 1130
New model for calculation of solvation free energies: correction of self-consistent reaction field continuum dielectric theory for short-range hydrogen-bonding effects B Marten, K Kim, C Cortis, RA Friesner, RB Murphy, MN Ringnalda, … The Journal of Physical Chemistry 100 (28), 11775-11788, 1996 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:L1USKYWJimsC Cited by: 1116
Origins of specificity in protein-DNA recognition R Rohs, X Jin, SM West, R Joshi, B Honig, RS Mann Annual review of biochemistry 79 (1), 233-269, 2010 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:ziOE8S1-AIUC Cited by: 1043
Calculation of the total electrostatic energy of a macromolecular system: solvation energies, binding energies, and conformational analysis MK Gilson, B Honig Proteins: Structure, Function, and Bioinformatics 4 (1), 7-18, 1988 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:e5wmG9Sq2KIC Cited by: 1038
Extending the applicability of the nonlinear Poisson− Boltzmann equation: multiple dielectric constants and multivalent ions W Rocchia, E Alexov, B Honig The Journal of Physical Chemistry B 105 (28), 6507-6514, 2001 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:YsMSGLbcyi4C Cited by: 997
Focusing of electric fields in the active site of Cu‐Zn superoxide dismutase: Effects of ionic strength and amino‐acid modification I Klapper, R Hagstrom, R Fine, K Sharp, B Honig Proteins: Structure, Function, and Bioinformatics 1 (1), 47-59, 1986 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:RJOyoaXV5v8C Cited by: 976
Electrostatic aspects of protein–protein interactions FB Sheinerman, R Norel, B Honig Current opinion in structural biology 10 (2), 153-159, 2000 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:mWEH9CqjF64C Cited by: 975
Structure-based prediction of protein–protein interactions on a genome-wide scale QC Zhang, D Petrey, L Deng, L Qiang, Y Shi, CA Thu, B Bisikirska, … Nature 490 (7421), 556-560, 2012 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:j7_hQOaDUrUC Cited by: 772
Reevaluation of the Born model of ion hydration AA Rashin, B Honig The journal of physical chemistry 89 (26), 5588-5593, 1985 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=KpeoVgAAAAJ&citationforview=KpeoVgAAAAJ:mB3voiENLucC Cited by: 739
Youtube Title: Harry Steenbock Lecturer - Barry Honig
Youtube Link: link
Youtube Channel Name: UW-Madison Department of Biochemistry
Youtube Channel Link: https://www.youtube.com/@UWBiochem
Harry Steenbock Lecturer - Barry Honig
Youtube Title: Harry Steenbock Lecture: Barry Honig
Youtube Link: link
Youtube Channel Name: UW-Madison Department of Biochemistry
Youtube Channel Link: https://www.youtube.com/@UWBiochem
Harry Steenbock Lecture: Barry Honig
Youtube Title: Barry Honig & Harvey Kesner Esq. Enjoying the '14 Roth Capital Conference
Youtube Link: link
Youtube Channel Name: Hindenburg Research
Youtube Channel Link: https://www.youtube.com/@hindenburgresearch4057
Barry Honig & Harvey Kesner Esq. Enjoying the '14 Roth Capital Conference
Youtube Title: Barry Honig Explains MyTruckScales at NISA Conference - Must Watch for the Trucking Industry
Youtube Link: link
Youtube Channel Name: TruckPay
Youtube Channel Link: https://www.youtube.com/@truckpay
Barry Honig Explains MyTruckScales at NISA Conference - Must Watch for the Trucking Industry
Youtube Title: CCMB SEMINAR 04/09/2014 - Barry Honig, PhD
Youtube Link: link
Youtube Channel Name: University of Michigan Computational Medicine and Bioinformatics
Youtube Channel Link: https://www.youtube.com/@universityofmichigancomput8877
CCMB SEMINAR 04/09/2014 - Barry Honig, PhD
Youtube Title: Barry Honig at the 2018 SD Cell Mapping Symposium
Youtube Link: link
Youtube Channel Name: Cancer Cell Map Initiative
Youtube Channel Link: https://www.youtube.com/@CancerCellMap
Barry Honig at the 2018 SD Cell Mapping Symposium
Youtube Title: SEC charges microcap fraudsters with market manipulation
Youtube Link: link
Youtube Channel Name: CNBC Television
Youtube Channel Link: https://www.youtube.com/@CNBCtelevision
SEC charges microcap fraudsters with market manipulation
Youtube Title: Using 3D structure to predict protein-protein and protein-ligand interactions - Barry Honig
Youtube Link: link
Youtube Channel Name: Rabadan Lab CUIMC, DSB, PMG
Youtube Channel Link: https://www.youtube.com/@rabadanlab6513
Using 3D structure to predict protein-protein and protein-ligand interactions - Barry Honig
Youtube Title: Building a Better Antibody
Youtube Link: link
Youtube Channel Name: Zuckerman Institute Podcasts
Youtube Channel Link: https://www.youtube.com/@zuckermaninstitutepodcasts8607
Building a Better Antibody
Youtube Title: Barry Allen Honig and The Southland Jukes Bliss Blues Jam
Youtube Link: link
Youtube Channel Name: AU Promotions
Youtube Channel Link: https://www.youtube.com/@AUPromotions
Barry Allen Honig and The Southland Jukes Bliss Blues Jam
Youtube Title: Conversation with Barry Prize winner Steven Koonin
Youtube Link: link
Youtube Channel Name: American Academy of Sciences & Letters
Youtube Channel Link: https://www.youtube.com/@AASL_Academy
Conversation with Barry Prize winner Steven Koonin
Youtube Title: Demo of Mark V Guitars by Barry Allen Honig
Youtube Link: link
Youtube Channel Name: markvguitars
Youtube Channel Link: https://www.youtube.com/@markvguitars
Demo of Mark V Guitars by Barry Allen Honig
Youtube Title: Barry Allen Honig Southland Jukes Famous Sunday Sessions - Highway Man
Youtube Link: link
Youtube Channel Name: AU Promotions
Youtube Channel Link: https://www.youtube.com/@AUPromotions
Barry Allen Honig Southland Jukes Famous Sunday Sessions - Highway Man
Youtube Title: Barry Allen Jamming Out in Hermosa Beach!
Youtube Link: link
Youtube Channel Name: Barry Allen Honig
Youtube Channel Link: https://www.youtube.com/@earthshaker61
Barry Allen Jamming Out in Hermosa Beach!
Youtube Title: "See About My Woman" guitar and vocal Barry Allen Honig
Youtube Link: link
Youtube Channel Name: Mark StJohnz Musik
Youtube Channel Link: https://www.youtube.com/@markstjohnzmusik8588
"See About My Woman" guitar and vocal Barry Allen Honig
Youtube Title: Mark V Guitars - Clips of Barry Allen Honig Demo
Youtube Link: link
Youtube Channel Name: markvguitars
Youtube Channel Link: https://www.youtube.com/@markvguitars
Mark V Guitars - Clips of Barry Allen Honig Demo
Youtube Title: Blues Jam - Long Beach - Barry Allen Honig - TheShyGuitarist
Youtube Link: link
Youtube Channel Name: theshyguitarist
Youtube Channel Link: https://www.youtube.com/@theshyguitarist
Blues Jam - Long Beach - Barry Allen Honig - TheShyGuitarist
Youtube Title: Barry Allen Honig Harbor Cruise Blues -- TheShyGuitarist
Youtube Link: link
Youtube Channel Name: theshyguitarist
Youtube Channel Link: https://www.youtube.com/@theshyguitarist
Barry Allen Honig Harbor Cruise Blues -- TheShyGuitarist
Youtube Title: Give me my Blues - Barry Allen & The Earthshakers @ Brix
Youtube Link: link
Youtube Channel Name: Barry Allen Honig
Youtube Channel Link: https://www.youtube.com/@earthshaker61
Give me my Blues - Barry Allen & The Earthshakers @ Brix
Summary: Barry H. Honig (born 1941) is an American biochemist, molecular biophysicist, and computational biophysicist, who develops theoretical methods and computer software for "analyzing the structure and function of biological macromolecules."
URL: https://en.wikipedia.org/wiki/BarryH.Honig
Page ID: 61803288
Categories:
Links:
Content: Barry H. Honig (born 1941) is an American biochemist, molecular biophysicist, and computational biophysicist, who develops theoretical methods and computer software for "analyzing the structure and function of biological macromolecules."
Education Honig graduated in 1963 from the Polytechnic Institute of Brooklyn with a B.Sc. summa cum laude in chemistry and in 1964 with a M.Sc. degree from Johns Hopkins University. He received his Ph.D. in chemical physics in 1968 from the Weizmann Institute with thesis advisor Joshua Jortner.
Career and research Honig was a postdoc under Martin Karplus at Harvard from 1968 to 1970 and at Columbia under Cyrus Levinthal from 1970 to 1973. He was an associate professor in the Chemistry Department of the Hebrew University, Jerusalem from 1973 to 1979 and in the Biophysics Department of the University of Illinois Urbana-Champaign from 1979 to1981. Since 1981, Honig has been a professor at the Columbia University Vagelos College of Physicians and Surgeons. He is currently a professor in the Departments of Systems Biology, Biochemistry and Molecular Biophysics and Medicine and is a member of the Zuckerman Mind, Brain Behavior Institute. He was an investigator for the Howard Hughes Medical Institute (HHMI) from 2000 to 2019. He has trained over 100 students and postdocs over the course of his career.
Honig is particularly noted for innovating methods to compute and display the electrostatic potentials of macromolecules based on their 3D structures. The computer programs DelPhi and GRASP were developed in his laboratory and are widely used by the academic and industrial communities. He has also made seminal contributions to the understanding of the spectroscopic and photochemical properties of visual pigments, to the computational prediction of protein structure and function, to the structural basis of protein-DNA interactions, and to the molecular principles that underlie cell-cell recognition. His current research focus in on the genome-wide prediction of protein-protein interactions and their dysregulation in human disease.
Awards and honors Honig is a member of the National Academy of Sciences, the American Academy of Arts and Sciences and Fellow of the American Association for Advancement of Science. He is recipient of numerous awards including: in 2007, the Alexander Hollaender Award in Biophysics from the National Academy for "pioneering theoretical and computational studies of electrostatic interactions in biological macromolecules and of the energetics of protein folding"; and in 2012, the DeLano Award in Computational Biosciences, from the American Society of Biochemistry and Molecular Biology and the Christian B. Anfinsen Award from the Protein Society. He is also an elected fellow of the International Society of Computational Biology (ISCB) and the Biophysical Society.
== References ==