doi.bio/janani_durairaj


Janani Durairaj

Overview

Janani Durairaj is a postdoctoral researcher at the University of Basel, working at the intersection of computational structural biology and machine learning. Her research focuses on developing methods to represent, explore, and understand protein structures for applications in drug discovery, vaccine design, and enzyme engineering.

Education

Durairaj completed a Bachelor of Engineering in Computer Science and a Master's in Biological Science from BITS Pilani, India. During her Master's, she undertook an internship in protein-protein interface prediction at the Bioinformatics group at Wageningen University. Following her Master's, she pursued a PhD in Bioinformatics at Wageningen University, graduating with the distinction cum laude. Her PhD thesis, titled "Computational approaches to discover novel enzymes for fragrance and flavour," combined homology modeling, structural and chemical feature extraction, and machine learning to predict and understand fragrance molecules produced by terpene synthases.

Awards and Recognition

Durairaj received the BioSB Young Investigator Award in 2022 for her contributions to the field of bioinformatics. She has also contributed to large-scale community-driven efforts, such as CASP15 and the Protein Universe Atlas.

Publications

Durairaj's notable publications include:

Current and Past Affiliations

Currently, Durairaj is a postdoctoral researcher with Prof. Torsten Schwede at the University of Basel, working on protein representations and benchmarking for computational drug discovery. Previously, she was a PhD candidate at Wageningen University, supervised by Dr. Aalt-Jan van Dijk and Prof. Dick de Ridder.

Janani Durairaj

Overview

Janani Durairaj is a postdoctoral researcher at the University of Basel, working at the intersection of computational structural biology and machine learning. She received the BioSB Young Investigator Award in 2022 for her PhD work in bioinformatics and has since contributed to community-driven projects such as CASP15 and the Protein Universe Atlas. Durairaj's research focuses on developing methods to represent, explore, and understand protein structures, with applications in drug discovery and vaccine design.

Education and Employment

Durairaj completed a Bachelor of Engineering in Computer Science and a Master's in Biological Science from BITS Pilani, India. During her master's program, she undertook an internship in protein-protein interface prediction at the Bioinformatics group at Wageningen University. Following her master's, she pursued a PhD in the same group, supervised by Dr. Aalt-Jan van Dijk and Prof. Dick de Ridder. Her doctoral research involved developing novel approaches that combined homology modeling, structural and chemical feature extraction, and machine learning to predict and understand fragrance molecules produced by terpene synthases. She successfully defended her PhD thesis, titled "Computational approaches to discover novel enzymes for fragrance and flavour", in September 2021, graduating with the distinction of cum laude.

Durairaj is currently a postdoctoral researcher with Prof. Torsten Schwede at the University of Basel, focusing on protein representations and benchmarking for computational drug discovery. She is part of the Protein Bioinformatics in 3D research group, where she works on developing efficient algorithms and software to represent and understand protein structures, with applications in areas such as enzyme engineering and drug discovery.

Research Contributions and Publications

Durairaj's research contributions are primarily in the field of computational structural biology and bioinformatics, with a focus on protein structure prediction and analysis. Her notable publications include:

Awards and Recognition

Youtube Videos

Youtube Title: VSC AlphaFold Event | Janani Durairaj | University of Basel

Youtube Link: link

Youtube Channel Name: Vlaams Supercomputer Centrum

Youtube Channel Link: https://www.youtube.com/@vschpc

VSC AlphaFold Event | Janani Durairaj | University of Basel

Youtube Title: #66 AlphaFold and shape-mers with Janani Durairaj

Youtube Link: link

Youtube Channel Name: the bioinformatics chat

Youtube Channel Link: https://www.youtube.com/@bioinfochat

#66 AlphaFold and shape-mers with Janani Durairaj

Youtube Title: Interview series of LIGATE project with Janani Durairaj Made by Headliner

Youtube Link: link

Youtube Channel Name: cheloniaswiss

Youtube Channel Link: https://www.youtube.com/@cheloniaswiss5993

Interview series of LIGATE project with Janani Durairaj Made by Headliner

Youtube Title: BrazWebinars: Dr Xavier Robin and Dr. Janani Durairaj, CAMEO Team, SIB, Universität Basel

Youtube Link: link

Youtube Channel Name: Bioinformática UFMG

Youtube Channel Link: https://www.youtube.com/@bioinformaticaufmg1410

BrazWebinars: Dr Xavier Robin and Dr. Janani Durairaj, CAMEO Team, SIB, Universität Basel

Youtube Title: CASP AI SIG April 14 2024 - Janani Durairaj

Youtube Link: link

Youtube Channel Name: Introduction to Bioinformatics by Arne Elofsson at Stockholm University

Youtube Channel Link: https://www.youtube.com/@introductiontobioinformati9910

CASP AI SIG April 14 2024 - Janani Durairaj

Youtube Title: Ester John Ramdeen - Jai Jaga Janani Bhaawani

Youtube Link: link

Youtube Channel Name: malini sarju

Youtube Channel Link: https://www.youtube.com/@mollysarj

Ester John Ramdeen - Jai Jaga Janani Bhaawani

Youtube Title: VSC AlphaFold Event

Youtube Link: link

Youtube Channel Name: Vlaams Supercomputer Centrum

Youtube Channel Link: https://www.youtube.com/@vschpc

VSC AlphaFold Event

Youtube Title: 30 June 2024

Youtube Link: link

Youtube Channel Name: Janani Durairaj

Youtube Channel Link: https://www.youtube.com/@jananidurairaj2465

30 June 2024

Youtube Title: #67 AlphaFold and variant effect prediction with Amelie Stein

Youtube Link: link

Youtube Channel Name: the bioinformatics chat

Youtube Channel Link: https://www.youtube.com/@bioinfochat

#67 AlphaFold and variant effect prediction with Amelie Stein

Youtube Title: Proceedings on Genes and Proteins - Dincer, Hoang Pham, Xuan, Durairaj - ECCB 2020

Youtube Link: link

Youtube Channel Name: ISCB

Youtube Channel Link: https://www.youtube.com/@ISCBtv

Proceedings on Genes and Proteins - Dincer, Hoang Pham, Xuan, Durairaj - ECCB 2020

Youtube Title: 3 June 2024

Youtube Link: link

Youtube Channel Name: Janani Durairaj

Youtube Channel Link: https://www.youtube.com/@jananidurairaj2465

3 June 2024

Youtube Title: University of Basel Researchers Discuss Botany Research on Duke Forest

Youtube Link: link

Youtube Channel Name: Duke Forest

Youtube Channel Link: https://www.youtube.com/@thedukeforest

University of Basel Researchers Discuss Botany Research on Duke Forest

Youtube Title: #65 AlphaFold and protein interactions with Pedro Beltrao

Youtube Link: link

Youtube Channel Name: the bioinformatics chat

Youtube Channel Link: https://www.youtube.com/@bioinfochat

#65 AlphaFold and protein interactions with Pedro Beltrao

Youtube Title: Artistic Inquiry and DNA storage

Youtube Link: link

Youtube Channel Name: Stanford Research Talks

Youtube Channel Link: https://www.youtube.com/@stanfordresearchtalks8541

Artistic Inquiry and DNA storage

Youtube Title: Nuances of Influencing Developer… - Neetu Jain, Janani Rajendiran, Samantha Carvalho & Tracy Ragan

Youtube Link: link

Youtube Channel Name: CNCF [Cloud Native Computing Foundation]

Youtube Channel Link: https://www.youtube.com/@cncf

Nuances of Influencing Developer... - Neetu Jain, Janani Rajendiran, Samantha Carvalho & Tracy Ragan

Youtube Title: Jay Jay Jagajanani Devi | Navratri 2020 | Aarya Ambekar

Youtube Link: link

Youtube Channel Name: AaryaSA Official

Youtube Channel Link: https://www.youtube.com/channel/UCOgBAzMJE2zBPs-rKKxixcw

Jay Jay Jagajanani Devi | Navratri 2020 | Aarya Ambekar