John Moult received his B.Sc. in Physics from the University of London in 1965 and his D.Phil. in Molecular Biophysics from the University of Oxford in 1970.
Dr. Moult is a researcher based at the Institute for Bioscience and Biotechnology Research (IBBR), administered by the University of Maryland on its Shady Grove campus in Rockville, MD. His lab's primary research focus is on the computational modeling of biological systems, including:
John Moult received his B.Sc. in Physics from the University of London in 1965 and his D.Phil. in Molecular Biophysics from the University of Oxford in 1970.
Dr. Moult is a researcher in the field of computational biology and is currently based at the University of Maryland. His laboratory focuses on computational modeling of biological systems, particularly in the areas of genome interpretation and protein structure modeling.
Moult's research interests include investigating the effects of missense single nucleotide variants on protein structure and function to understand their role in human diseases, such as cystic fibrosis, sickle cell anemia, and cancer. He also works on integrating knowledge of the biological mechanisms underlying the relationship between human genetic variation and complex trait diseases like Alzheimer's, diabetes, and Crohn's disease.
Moult's lab utilizes machine learning, evolutionary, and protein structure information to develop new computational methods for determining the impact of genetic variants. They also work on novel neural network architectures derived from deep biological knowledge to probe aspects of disease mechanisms, including drug target evaluation and personalized medicine based on a patient's genome sequence.
John Moult received a B.Sc. in Physics from the University of London in 1965 and a D.Phil. in Molecular Biophysics from the University of Oxford in 1970.
Dr. Moult is a researcher focused on computational modeling of biological systems. He currently works at the University of Maryland, where he holds the position of Group Guru and is leading a lab conducting research on the computational modeling of biological systems.
Moult's research interests include investigating the effects of missense single nucleotide variants on protein structure and function to understand their role in human diseases, particularly in the context of rare Mendelian diseases and cancers. He also works on integrating knowledge of the biological mechanisms underlying the relationship between human genetic variation and complex trait diseases such as Alzheimer's, diabetes, and Crohn's disease.
Moult's lab develops new computational methods, including machine learning and evolutionary and protein structure information, to determine the impact of genetic variants on protein function. They also work on integrating knowledge of disease mechanisms to develop a formal description of biological mechanisms and capture what is known (and not known) about key genotype/disease phenotype relationships.
In addition, Moult's group is developing a new neural network protocol, where the network architecture is dictated by the disease mechanism, allowing for the probing of various aspects of a disease, such as evaluation of potential drug targets and drug response based on a patient's genetic variants.
Moult is also involved in community experiments to advance computational biology, participating in critical assessment experiments such as Critical Assessment of Structure Prediction (CASP) and Critical Assessment of Genome Interpretation (CAGI).
John Moult University of Maryland N/A SNPs, protein structure, and disease Z Wang, J Moult Human mutation 17 (4), 263-270, 2001 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:eflP2zaiRacC Cited by: 974
Genetic algorithms for protein folding simulations R Unger, J Moult Journal of molecular biology 231 (1), 75-81, 1993 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:qxL8FJ1GzNcC Cited by: 876
CAPRI: a critical assessment of predicted interactions J Janin, K Henrick, J Moult, LT Eyck, MJE Sternberg, S Vajda, I Vakser, … Proteins: Structure, Function, and Bioinformatics 52 (1), 2-9, 2003 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:J_g5lzvAfSwC Cited by: 787
A large‐scale experiment to assess protein structure prediction methods J Moult, JT Pedersen, R Judson, K Fidelis Proteins: Structure, Function, and Bioinformatics 23 (3), ii-iv, 1995 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:hC7cP41nSMkC Cited by: 672
A decade of CASP: progress, bottlenecks and prognosis in protein structure prediction J Moult Current opinion in structural biology 15 (3), 285-289, 2005 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:B3FOqHPlNUQC Cited by: 643
The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses BA Methé, KE Nelson, JW Deming, B Momen, E Melamud, X Zhang, … Proceedings of the National Academy of Sciences 102 (31), 10913-10918, 2005 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:roLk4NBRz8UC Cited by: 602
An all-atom distance-dependent conditional probability discriminatory function for protein structure prediction R Samudrala, J Moult Journal of molecular biology 275 (5), 895-916, 1998 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:CHSYGLWDkRkC Cited by: 580
SNPs3D: candidate gene and SNP selection for association studies P Yue, E Melamud, J Moult BMC bioinformatics 7, 1-15, 2006 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:JV2RwH3_ST0C Cited by: 564
Loss of protein structure stability as a major causative factor in monogenic disease P Yue, Z Li, J Moult Journal of molecular biology 353 (2), 459-473, 2005 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:lSLTfruPkqcC Cited by: 555
Critical assessment of methods of protein structure prediction (CASP)—Round XIII A Kryshtafovych, T Schwede, M Topf, K Fidelis, J Moult Proteins: Structure, Function, and Bioinformatics 87 (12), 1011-1020, 2019 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:0KyAp5RtaNEC Cited by: 509
Completeness in structural genomics D Vitkup, E Melamud, J Moult, C Sander nature structural biology 8 (6), 559-566, 2001 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:LkGwnXOMwfcC Cited by: 490
Critical assessment of methods of protein structure prediction (CASP)—round x J Moult, K Fidelis, A Kryshtafovych, T Schwede, A Tramontano Proteins: Structure, Function, and Bioinformatics 82, 1-6, 2014 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:3s1wT3WcHBgC Cited by: 489
Bacterial Resistance to β-Lactam Antibiotics: Crystal Structure of β-Lactamase from Staphylococcus aureus PC1 at 2.5 Å Resolution O Herzberg, J Moult Science 236 (4802), 694-701, 1987 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:dhFuZR0502QC Cited by: 450
Critical assessment of methods of protein structure prediction (CASP): round III J Moult, T Hubbard, K Fidelis, JT Pedersen Proteins: Structure, Function, and Bioinformatics 37 (S3), 2-6, 1999 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:0EnyYjriUFMC Cited by: 424
Critical assessment of methods of protein structure prediction (CASP)—Round XII J Moult, K Fidelis, A Kryshtafovych, T Schwede, A Tramontano Proteins: Structure, Function, and Bioinformatics 86 (S1), 7-15, 2018 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:P5F9QuxV20EC Cited by: 375
Critical assessment of methods of protein structure prediction (CASP)—Round XIV A Kryshtafovych, T Schwede, M Topf, K Fidelis, J Moult Proteins: Structure, Function, and Bioinformatics 89 (12), 1607-1617, 2021 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:tYavs44e6CUC Cited by: 369
A model for the Ca2+-induced conformational transition of troponin C. A trigger for muscle contraction. O Herzberg, J Moult, MN James Journal of Biological Chemistry 261 (6), 2638-2644, 1986 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:HDshCWvjkbEC Cited by: 369
Processing and analysis of CASP3 protein structure predictions A Zemla, Č Venclovas, J Moult, K Fidelis Proteins: Structure, Function, and Bioinformatics 37 (S3), 22-29, 1999 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:UxriW0iASnsC Cited by: 352
Identification and analysis of deleterious human SNPs P Yue, J Moult Journal of molecular biology 356 (5), 1263-1274, 2006 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:YsMSGLbcyi4C Cited by: 311
Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008 M Michino, E Abola, GPCR Dock 2008 Participants, CL Brooks III, … Nature Reviews Drug Discovery 8 (6), 455-463, 2009 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:iH-uZ7U-co4C Cited by: 303
John Moult University of Maryland N/A SNPs, protein structure, and disease Z Wang, J Moult Human mutation 17 (4), 263-270, 2001 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:eflP2zaiRacC Cited by: 974
Genetic algorithms for protein folding simulations R Unger, J Moult Journal of molecular biology 231 (1), 75-81, 1993 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:qxL8FJ1GzNcC Cited by: 876
CAPRI: a critical assessment of predicted interactions J Janin, K Henrick, J Moult, LT Eyck, MJE Sternberg, S Vajda, I Vakser, … Proteins: Structure, Function, and Bioinformatics 52 (1), 2-9, 2003 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:J_g5lzvAfSwC Cited by: 787
A large‐scale experiment to assess protein structure prediction methods J Moult, JT Pedersen, R Judson, K Fidelis Proteins: Structure, Function, and Bioinformatics 23 (3), ii-iv, 1995 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:hC7cP41nSMkC Cited by: 672
A decade of CASP: progress, bottlenecks and prognosis in protein structure prediction J Moult Current opinion in structural biology 15 (3), 285-289, 2005 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:B3FOqHPlNUQC Cited by: 643
The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses BA Methé, KE Nelson, JW Deming, B Momen, E Melamud, X Zhang, … Proceedings of the National Academy of Sciences 102 (31), 10913-10918, 2005 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:roLk4NBRz8UC Cited by: 602
An all-atom distance-dependent conditional probability discriminatory function for protein structure prediction R Samudrala, J Moult Journal of molecular biology 275 (5), 895-916, 1998 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:CHSYGLWDkRkC Cited by: 580
SNPs3D: candidate gene and SNP selection for association studies P Yue, E Melamud, J Moult BMC bioinformatics 7, 1-15, 2006 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:JV2RwH3_ST0C Cited by: 564
Loss of protein structure stability as a major causative factor in monogenic disease P Yue, Z Li, J Moult Journal of molecular biology 353 (2), 459-473, 2005 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:lSLTfruPkqcC Cited by: 555
Critical assessment of methods of protein structure prediction (CASP)—Round XIII A Kryshtafovych, T Schwede, M Topf, K Fidelis, J Moult Proteins: Structure, Function, and Bioinformatics 87 (12), 1011-1020, 2019 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:0KyAp5RtaNEC Cited by: 509
Completeness in structural genomics D Vitkup, E Melamud, J Moult, C Sander nature structural biology 8 (6), 559-566, 2001 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:LkGwnXOMwfcC Cited by: 490
Critical assessment of methods of protein structure prediction (CASP)—round x J Moult, K Fidelis, A Kryshtafovych, T Schwede, A Tramontano Proteins: Structure, Function, and Bioinformatics 82, 1-6, 2014 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:3s1wT3WcHBgC Cited by: 489
Bacterial Resistance to β-Lactam Antibiotics: Crystal Structure of β-Lactamase from Staphylococcus aureus PC1 at 2.5 Å Resolution O Herzberg, J Moult Science 236 (4802), 694-701, 1987 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:dhFuZR0502QC Cited by: 450
Critical assessment of methods of protein structure prediction (CASP): round III J Moult, T Hubbard, K Fidelis, JT Pedersen Proteins: Structure, Function, and Bioinformatics 37 (S3), 2-6, 1999 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:0EnyYjriUFMC Cited by: 424
Critical assessment of methods of protein structure prediction (CASP)—Round XII J Moult, K Fidelis, A Kryshtafovych, T Schwede, A Tramontano Proteins: Structure, Function, and Bioinformatics 86 (S1), 7-15, 2018 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:P5F9QuxV20EC Cited by: 375
Critical assessment of methods of protein structure prediction (CASP)—Round XIV A Kryshtafovych, T Schwede, M Topf, K Fidelis, J Moult Proteins: Structure, Function, and Bioinformatics 89 (12), 1607-1617, 2021 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:tYavs44e6CUC Cited by: 369
A model for the Ca2+-induced conformational transition of troponin C. A trigger for muscle contraction. O Herzberg, J Moult, MN James Journal of Biological Chemistry 261 (6), 2638-2644, 1986 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:HDshCWvjkbEC Cited by: 369
Processing and analysis of CASP3 protein structure predictions A Zemla, Č Venclovas, J Moult, K Fidelis Proteins: Structure, Function, and Bioinformatics 37 (S3), 22-29, 1999 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:UxriW0iASnsC Cited by: 352
Identification and analysis of deleterious human SNPs P Yue, J Moult Journal of molecular biology 356 (5), 1263-1274, 2006 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:YsMSGLbcyi4C Cited by: 311
Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008 M Michino, E Abola, GPCR Dock 2008 Participants, CL Brooks III, … Nature Reviews Drug Discovery 8 (6), 455-463, 2009 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:iH-uZ7U-co4C Cited by: 303
John Moult University of Maryland N/A SNPs, protein structure, and disease Z Wang, J Moult Human mutation 17 (4), 263-270, 2001 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:eflP2zaiRacC Cited by: 974
Genetic algorithms for protein folding simulations R Unger, J Moult Journal of molecular biology 231 (1), 75-81, 1993 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:qxL8FJ1GzNcC Cited by: 876
CAPRI: a critical assessment of predicted interactions J Janin, K Henrick, J Moult, LT Eyck, MJE Sternberg, S Vajda, I Vakser, … Proteins: Structure, Function, and Bioinformatics 52 (1), 2-9, 2003 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:J_g5lzvAfSwC Cited by: 787
A large‐scale experiment to assess protein structure prediction methods J Moult, JT Pedersen, R Judson, K Fidelis Proteins: Structure, Function, and Bioinformatics 23 (3), ii-iv, 1995 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:hC7cP41nSMkC Cited by: 672
A decade of CASP: progress, bottlenecks and prognosis in protein structure prediction J Moult Current opinion in structural biology 15 (3), 285-289, 2005 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:B3FOqHPlNUQC Cited by: 643
The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses BA Methé, KE Nelson, JW Deming, B Momen, E Melamud, X Zhang, … Proceedings of the National Academy of Sciences 102 (31), 10913-10918, 2005 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:roLk4NBRz8UC Cited by: 602
An all-atom distance-dependent conditional probability discriminatory function for protein structure prediction R Samudrala, J Moult Journal of molecular biology 275 (5), 895-916, 1998 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:CHSYGLWDkRkC Cited by: 580
SNPs3D: candidate gene and SNP selection for association studies P Yue, E Melamud, J Moult BMC bioinformatics 7, 1-15, 2006 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:JV2RwH3_ST0C Cited by: 564
Loss of protein structure stability as a major causative factor in monogenic disease P Yue, Z Li, J Moult Journal of molecular biology 353 (2), 459-473, 2005 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:lSLTfruPkqcC Cited by: 555
Critical assessment of methods of protein structure prediction (CASP)—Round XIII A Kryshtafovych, T Schwede, M Topf, K Fidelis, J Moult Proteins: Structure, Function, and Bioinformatics 87 (12), 1011-1020, 2019 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:0KyAp5RtaNEC Cited by: 509
Completeness in structural genomics D Vitkup, E Melamud, J Moult, C Sander nature structural biology 8 (6), 559-566, 2001 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:LkGwnXOMwfcC Cited by: 490
Critical assessment of methods of protein structure prediction (CASP)—round x J Moult, K Fidelis, A Kryshtafovych, T Schwede, A Tramontano Proteins: Structure, Function, and Bioinformatics 82, 1-6, 2014 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:3s1wT3WcHBgC Cited by: 489
Bacterial Resistance to β-Lactam Antibiotics: Crystal Structure of β-Lactamase from Staphylococcus aureus PC1 at 2.5 Å Resolution O Herzberg, J Moult Science 236 (4802), 694-701, 1987 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:dhFuZR0502QC Cited by: 450
Critical assessment of methods of protein structure prediction (CASP): round III J Moult, T Hubbard, K Fidelis, JT Pedersen Proteins: Structure, Function, and Bioinformatics 37 (S3), 2-6, 1999 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:0EnyYjriUFMC Cited by: 424
Critical assessment of methods of protein structure prediction (CASP)—Round XII J Moult, K Fidelis, A Kryshtafovych, T Schwede, A Tramontano Proteins: Structure, Function, and Bioinformatics 86 (S1), 7-15, 2018 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:P5F9QuxV20EC Cited by: 375
Critical assessment of methods of protein structure prediction (CASP)—Round XIV A Kryshtafovych, T Schwede, M Topf, K Fidelis, J Moult Proteins: Structure, Function, and Bioinformatics 89 (12), 1607-1617, 2021 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:tYavs44e6CUC Cited by: 369
A model for the Ca2+-induced conformational transition of troponin C. A trigger for muscle contraction. O Herzberg, J Moult, MN James Journal of Biological Chemistry 261 (6), 2638-2644, 1986 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:HDshCWvjkbEC Cited by: 369
Processing and analysis of CASP3 protein structure predictions A Zemla, Č Venclovas, J Moult, K Fidelis Proteins: Structure, Function, and Bioinformatics 37 (S3), 22-29, 1999 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:UxriW0iASnsC Cited by: 352
Identification and analysis of deleterious human SNPs P Yue, J Moult Journal of molecular biology 356 (5), 1263-1274, 2006 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:YsMSGLbcyi4C Cited by: 311
Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008 M Michino, E Abola, GPCR Dock 2008 Participants, CL Brooks III, … Nature Reviews Drug Discovery 8 (6), 455-463, 2009 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:iH-uZ7U-co4C Cited by: 303
John Moult
University of Maryland
N/A
SNPs, protein structure, and disease Z Wang, J Moult Human mutation 17 (4), 263-270, 2001 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:eflP2zaiRacC
Genetic algorithms for protein folding simulations R Unger, J Moult Journal of molecular biology 231 (1), 75-81, 1993 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:qxL8FJ1GzNcC
CAPRI: a critical assessment of predicted interactions J Janin, K Henrick, J Moult, LT Eyck, MJE Sternberg, S Vajda, I Vakser, … Proteins: Structure, Function, and Bioinformatics 52 (1), 2-9, 2003 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:J_g5lzvAfSwC
A large‐scale experiment to assess protein structure prediction methods J Moult, JT Pedersen, R Judson, K Fidelis Proteins: Structure, Function, and Bioinformatics 23 (3), ii-iv, 1995 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:hC7cP41nSMkC
A decade of CASP: progress, bottlenecks and prognosis in protein structure prediction J Moult Current opinion in structural biology 15 (3), 285-289, 2005 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:B3FOqHPlNUQC
The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses BA Methé, KE Nelson, JW Deming, B Momen, E Melamud, X Zhang, … Proceedings of the National Academy of Sciences 102 (31), 10913-10918, 2005 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:roLk4NBRz8UC
An all-atom distance-dependent conditional probability discriminatory function for protein structure prediction R Samudrala, J Moult Journal of molecular biology 275 (5), 895-916, 1998 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:CHSYGLWDkRkC
SNPs3D: candidate gene and SNP selection for association studies P Yue, E Melamud, J Moult BMC bioinformatics 7, 1-15, 2006 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:JV2RwH3_ST0C
Loss of protein structure stability as a major causative factor in monogenic disease P Yue, Z Li, J Moult Journal of molecular biology 353 (2), 459-473, 2005 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:lSLTfruPkqcC
Critical assessment of methods of protein structure prediction (CASP)—Round XIII A Kryshtafovych, T Schwede, M Topf, K Fidelis, J Moult Proteins: Structure, Function, and Bioinformatics 87 (12), 1011-1020, 2019 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:0KyAp5RtaNEC
Completeness in structural genomics D Vitkup, E Melamud, J Moult, C Sander nature structural biology 8 (6), 559-566, 2001 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:LkGwnXOMwfcC
Critical assessment of methods of protein structure prediction (CASP)—round x J Moult, K Fidelis, A Kryshtafovych, T Schwede, A Tramontano Proteins: Structure, Function, and Bioinformatics 82, 1-6, 2014 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:3s1wT3WcHBgC
Bacterial Resistance to β-Lactam Antibiotics: Crystal Structure of β-Lactamase from Staphylococcus aureus PC1 at 2.5 Å Resolution O Herzberg, J Moult Science 236 (4802), 694-701, 1987 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:dhFuZR0502QC
Critical assessment of methods of protein structure prediction (CASP): round III J Moult, T Hubbard, K Fidelis, JT Pedersen Proteins: Structure, Function, and Bioinformatics 37 (S3), 2-6, 1999 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:0EnyYjriUFMC
Critical assessment of methods of protein structure prediction (CASP)—Round XII J Moult, K Fidelis, A Kryshtafovych, T Schwede, A Tramontano Proteins: Structure, Function, and Bioinformatics 86 (S1), 7-15, 2018 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:P5F9QuxV20EC
Critical assessment of methods of protein structure prediction (CASP)—Round XIV A Kryshtafovych, T Schwede, M Topf, K Fidelis, J Moult Proteins: Structure, Function, and Bioinformatics 89 (12), 1607-1617, 2021 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:tYavs44e6CUC
A model for the Ca2+-induced conformational transition of troponin C. A trigger for muscle contraction. O Herzberg, J Moult, MN James Journal of Biological Chemistry 261 (6), 2638-2644, 1986 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:HDshCWvjkbEC
Processing and analysis of CASP3 protein structure predictions A Zemla, Č Venclovas, J Moult, K Fidelis Proteins: Structure, Function, and Bioinformatics 37 (S3), 22-29, 1999 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:UxriW0iASnsC
Identification and analysis of deleterious human SNPs P Yue, J Moult Journal of molecular biology 356 (5), 1263-1274, 2006 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:YsMSGLbcyi4C
Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008 M Michino, E Abola, GPCR Dock 2008 Participants, CL Brooks III, … Nature Reviews Drug Discovery 8 (6), 455-463, 2009 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=7r7qIkAAAAJ&citationforview=7r7qIkAAAAJ:iH-uZ7U-co4C
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PSW 2445 The First Serious Problem Solved by AI | John Moult
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Function KEYNOTE: Community Driven Critical Assessment... - John Moult - Function - ISMB/ECCB 2017
Youtube Title: Talk by Prof. John Moult on "Solving the protein folding problem through AI"
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Talk by Prof. John Moult on "Solving the protein folding problem through AI"
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Youtube Channel Name: CASP-SIG Conformational Ensembles of Protein
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Youtube Title: Lessons learned from 10 years of CAGI experiments - John Moult - VarI - Abstract - ISMB 2022
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Youtube Channel Name: ISCB
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Lessons learned from 10 years of CAGI experiments - John Moult - VarI - Abstract - ISMB 2022
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Youtube Channel Link: https://www.youtube.com/@everythingyouneedtoknow1709
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Youtube Channel Link: https://www.youtube.com/@CASPRNASIG
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Youtube Title: The 20th Annual Wiley Prize in Biomedical Sciences
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Youtube Channel Link: https://www.youtube.com/@everythingyouneedtoknow1709
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