Neil King
Assistant Professor, UW Biochemistry / Institute for Protein Design
http://kinglab.ipd.uw.edu/
Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding TN Starr, AJ Greaney, SK Hilton, D Ellis, KHD Crawford, AS Dingens, … cell 182 (5), 1295-1310. e20, 2020 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=qhS5wYIAAAAJ&citationforview=qhS5wYIAAAAJ:rO6llkc54NcC
Computational design of self-assembling protein nanomaterials with atomic level accuracy NP King, W Sheffler, MR Sawaya, BS Vollmar, JP Sumida, I André, … Science 336 (6085), 1171-1174, 2012 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=qhS5wYIAAAAJ&citationforview=qhS5wYIAAAAJ:qjMakFHDy7sC
Protocol and reagents for pseudotyping lentiviral particles with SARS-CoV-2 spike protein for neutralization assays KHD Crawford, R Eguia, AS Dingens, AN Loes, KD Malone, CR Wolf, … Viruses 12 (5), 513, 2020 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=qhS5wYIAAAAJ&citationforview=qhS5wYIAAAAJ:vV6vV6tmYwMC
Functional SARS-CoV-2-specific immune memory persists after mild COVID-19 LB Rodda, J Netland, L Shehata, KB Pruner, PA Morawski, CD Thouvenel, … Cell 184 (1), 169-183. e17, 2021 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=qhS5wYIAAAAJ&citationforview=qhS5wYIAAAAJ:HoB7MX3m0LUC
Robust deep learning–based protein sequence design using ProteinMPNN J Dauparas, I Anishchenko, N Bennett, H Bai, RJ Ragotte, LF Milles, … Science 378 (6615), 49-56, 2022 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=qhS5wYIAAAAJ&citationforview=qhS5wYIAAAAJ:J-pR_7NvFogC
Accurate design of co-assembling multi-component protein nanomaterials NP King, JB Bale, W Sheffler, DE McNamara, S Gonen, T Gonen, … Nature 510 (7503), 103-108, 2014 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=qhS5wYIAAAAJ&citationforview=qhS5wYIAAAAJ:UebtZRa9Y70C
Accurate design of megadalton-scale two-component icosahedral protein complexes JB Bale, S Gonen, Y Liu, W Sheffler, D Ellis, C Thomas, D Cascio, … Science 353 (6297), 389-394, 2016 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=qhS5wYIAAAAJ&citationforview=qhS5wYIAAAAJ:kcbZDykSQC
Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2 AC Walls, B Fiala, A Schäfer, S Wrenn, MN Pham, M Murphy, … Cell 183 (5), 1367-1382. e17, 2020 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=qhS5wYIAAAAJ&citationforview=qhS5wYIAAAAJ:pqnbT2bcN3wC
Design of a hyperstable 60-subunit protein icosahedron Y Hsia, JB Bale, S Gonen, D Shi, W Sheffler, KK Fong, U Nattermann, … Nature 535 (7610), 136-139, 2016 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=qhS5wYIAAAAJ&citationforview=qhS5wYIAAAAJ:YOwf2qJgpHMC
Induction of potent neutralizing antibody responses by a designed protein nanoparticle vaccine for respiratory syncytial virus J Marcandalli, B Fiala, S Ols, M Perotti, W de van der Schueren, J Snijder, … Cell 176 (6), 1420-1431. e17, 2019 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=qhS5wYIAAAAJ&citationforview=qhS5wYIAAAAJ:j3f4tGmQtD8C
Dynamics of neutralizing antibody titers in the months after severe acute respiratory syndrome coronavirus 2 infection KHD Crawford, AS Dingens, R Eguia, CR Wolf, N Wilcox, JK Logue, … The Journal of infectious diseases 223 (2), 197-205, 2021 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=qhS5wYIAAAAJ&citationforview=qhS5wYIAAAAJ:g5m5HwL7SMYC
Adjuvanting a subunit COVID-19 vaccine to induce protective immunity PS Arunachalam, AC Walls, N Golden, C Atyeo, S Fischinger, C Li, P Aye, … Nature 594 (7862), 253-258, 2021 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=qhS5wYIAAAAJ&citationforview=qhS5wYIAAAAJ:1sJd4Hv_s6UC
Quadrivalent influenza nanoparticle vaccines induce broad protection S Boyoglu-Barnum, D Ellis, RA Gillespie, GB Hutchinson, YJ Park, … Nature 592 (7855), 623-628, 2021 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=qhS5wYIAAAAJ&citationforview=qhS5wYIAAAAJ:xtRiw3GOFMkC
Evolution of a designed protein assembly encapsulating its own RNA genome GL Butterfield, MJ Lajoie, HH Gustafson, DL Sellers, U Nattermann, … Nature 552 (7685), 415-420, 2017 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=qhS5wYIAAAAJ&citationforview=qhS5wYIAAAAJ:qUcmZB5y_30C
Principles for designing ordered protein assemblies YT Lai, NP King, TO Yeates Trends in Cell Biology 22 (12), 653-661, 2012 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=qhS5wYIAAAAJ&citationforview=qhS5wYIAAAAJ:IjCSPb-OGe4C
Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle PJM Brouwer, A Antanasijevic, Z Berndsen, A Yasmeen, B Fiala, TPL Bijl, … Nature Communications 10 (1), 4272, 2019 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=qhS5wYIAAAAJ&citationforview=qhS5wYIAAAAJ:k_IJM867U9cC
Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection PJM Brouwer, M Brinkkemper, P Maisonnasse, N Dereuddre-Bosquet, … Cell 184 (5), 1188-1200. e19, 2021 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=qhS5wYIAAAAJ&citationforview=qhS5wYIAAAAJ:u_35RYKgDlwC
Identification of rare slipknots in proteins and their implications for stability and folding NP King, EO Yeates, TO Yeates Journal of molecular biology 373 (1), 153-166, 2007 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=qhS5wYIAAAAJ&citationforview=qhS5wYIAAAAJ:u-x6o8ySG0sC
Structure and folding of a designed knotted protein NP King, AW Jacobitz, MR Sawaya, L Goldschmidt, TO Yeates Proceedings of the National Academy of Sciences 107 (48), 20732-20737, 2010 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=qhS5wYIAAAAJ&citationforview=qhS5wYIAAAAJ:9yKSN-GCB0IC
Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines AC Walls, MC Miranda, A Schäfer, MN Pham, A Greaney, … Cell 184 (21), 5432-5447. e16, 2021 Link: https://scholar.google.com/citations?viewop=viewcitation&hl=en&user=qhS5wYIAAAAJ&citationforview=qhS5wYIAAAAJ:abG-DnoFyZgC
David Baker googlescholarauthorid davidbaker.md:UKqIqRsAAAAJ
David Veesler googlescholarauthorid davidveesler.md:ehJAeL8AAAAJ
Will Sheffler googlescholarauthorid willsheffler.md:T_8K-XEAAAAJ
Todd O. Yeates googlescholarauthorid toddo._yeates.md:vuAMQKYAAAAJ
Jesse D. Bloom googlescholarauthorid jessed.bloom.md:S12xeQAAAAJ
Jacob Bale googlescholarauthorid jacobbale.md:_2TCqEQAAAAJ
Brooke Fiala googlescholarauthorid brookefiala.md:zqoTBVQAAAAJ
Yang Hsia googlescholarauthorid yanghsia.md:uK2gkykAAAAJ
Tamir Gonen googlescholarauthorid tamirgonen.md:tsf-w3UAAAAJ
Katharine H. D. Crawford googlescholarauthorid katharineh.d.crawford.md:aAwVaH8AAAAJ
M. Alejandra Tortorici googlescholarauthorid m.alejandra_tortorici.md:nYicpOYAAAAJ
Rachel Eguia googlescholarauthorid racheleguia.md:qTyqAAQAAAAJ
Helen Y Chu googlescholarauthorid heleny_chu.md:pBFRfNoAAAAJ
Una Nattermann googlescholarauthorid unanattermann.md:32UJMAAAAJ
Shane Gonen googlescholarauthorid shanegonen.md:qZm-DQ8AAAAJ
Caitlin R. Wolf googlescholarauthorid caitlinr._wolf.md:vmYvyJUAAAAJ
Banumathi Sankaran googlescholarauthorid banumathisankaran.md:ahvfYIgAAAAJ
Tyler Starr googlescholarauthorid tylerstarr.md:vqekw9MAAAAJ
Masaru Kanekiyo googlescholarauthorid masarukanekiyo.md:Nhq0d_YAAAAJ
Marion Pepper googlescholarauthorid marionpepper.md:44bU26IAAAAJ