doi.bio/inceptive

Inceptive Nucleics

Summary

Inceptive is a privately-held, venture capital-backed company that designs RNA molecules using large-scale deep learning and high-throughput experiments. The company aims to improve the lives of billions of people worldwide by developing powerful biological software to create novel and accessible medicines and biotechnologies.

Competitors

Syros Pharmaceuticals Isomorphic Labs Insitro Recursion Inceptive EvolutionaryScale

Locations

Inceptive has offices in the following locations:

Employees

Inceptive has approximately 40 employees, including:

Executive Officers and Board Members

Inceptive's executive team includes:

Funding and Investors

Inceptive has raised a total of $100 million in funding as of its Series A round in October 2023. The company's investors include:

Services and Solutions

Inceptive offers consulting and engineering services, helping businesses with digital transformation and startup solutions. They specialize in:


Inceptive Biological Software is one or more synthetic molecules that execute complex functions, specified from a program, in a biological system.

We are creating tools to develop increasingly powerful biological software for the design of novel, broadly accessible medicines and biotechnologies previously out of reach.

Our antedisciplinary team of scientists, machine learning researchers, engineers and entrepreneurs is growing. If you are excited to learn, teach, discover, and create together in pursuit of learning life's languages to improve the lives of billions of people around the world, apply here. info@inceptive.life +1 (650) 507-4490 Wet research and development: 3440 Hillview Ave, D100, Palo Alto, CA, 94304, USA Dry research and development: Planet Earth.


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The company’s CEO, Jakob Uszkoreit, a former Google senior staff software engineer who pioneered work on large-language models, says the company will license new proteins its AI develops for clinical trials. There are already 310 pilots occupying the continuum from pre-clinical to clinical trials.

Inceptive Wants Proteins Designed by AI Algorithms to Instruct Human Body Cells According to Uszkoreit, the new drugs will instruct cells in the human body to execute instructions similar to how a computer runs code. By the decade’s end, there will be about 700 mRNA-based drugs.

“We want to maximize the positive impact of this type of work in AI,” Uszkoreit said.

The CEO’s time at Google involved developing machine-learning tools to understand natural language. His work helped Google’s DeepMind create an algorithm to predict the structure of almost every known protein.

Proteins are chains of chemical compounds called amino acids that twist into shapes depending on their purpose. The human body naturally produces around 20,000 proteins for, among other things, digesting food and transporting oxygen.

Biotech Inceptive to create proteins from an AI aglorithm.Six protein shapes a DeepMind’s AI algorithm created | Source: New York Times Read here about how novel products are using AI automation to streamline workflows.

Inceptive has the backing of Silicon Valley venture capitalists (VCs) Andreessen Horowitz and Nvidia Corporation’s venture capital arm, NVentures. The latter invested $50 million in another drug discovery company, Recursion Pharmaceuticals, based in Utah.

Inceptive’s deal with Nvidia will give the chipmaker an equity stake and avail its cutting-edge tools to the Palo Alto-based startup company. Other notable firms in the AI-biotech space include Insilico, a company in the mid-stage clinical trial of an AI-synthesized treatment for lung disease in late June.

I-Biotech Investment Signals a Shift in VC Spending The entrance of big-tech venture capitalists into pharma marks a notable shift in the flow of VC money. Earlier this year, Morgan Stanley predicted a $50 billion opportunity for AI in Big Pharma.

AI is also making its way into the finance industry. Find out how here.

But the industry is far from being a sure bet. In May, Benevolent AI, a London-based biotech startup, said it would lay off 180 staff after its main drug candidate failed.

Critics have also warned the technology is overhyped. Moreover, regulators like the US Federal Drug Administration have yet to approve a single AI-designed drug.

Got something to say about the development of AI-generated proteins and drugs by Inceptive or anything else? Write to us or join the discussion on our Telegram channel. You can also catch us on TikTok, Facebook, or X (Twitter).

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Share on Twitter Share on Email Share on Linkedin Share on Google News David-Thomas.jpg David Thomas READ FULL BIO David Thomas graduated from the University of Kwa-Zulu Natal in Durban, South Africa, with an Honors degree in electronic engineering. He worked as an engineer for eight years, developing software for industrial processes at South African automation specialist Autotronix (Pty) Ltd., mining control systems for AngloGold Ashanti, and consumer products at Inhep Digital Security, a domestic security company wholly owned by Swedish conglomerate Assa Abloy. He has experience writing software in C,… RELATED NEWS Markets Analysis Ripple (XRP) Holders Need to Do More Than Just Hope for Price Recovery
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ME: Please extract the article from this

[AI]: Former Google Employee Raises $100 Million to Bring AI to Big Pharma

In a significant move for the biotech and AI industries, Palo Alto-based startup Inceptive has secured a whopping $100 million in funding to pioneer the development of unique vaccine proteins utilizing artificial intelligence (AI). Spearheaded by former Google senior staff software engineer Jakok Uszkoreit, Inceptive aims to replicate and potentially surpass the groundbreaking success seen in mRNA vaccines like those deployed against COVID-19.

Jakob Uszkoreit, who has a notable background in working on large language models at Google, has outlined ambitious plans for his venture. Inceptive will focus on licensing the proteins created by its AI for use in clinical trials. Currently, the company has an impressive 310 pilots, ranging from pre-clinical to clinical development stages, earmarked for its novel approach. The strategic use of AI in designing proteins presents a paradigm shift, intending to instruct human body cells to execute specific functions, similar to running code on a computer. By the end of the decade, Uszkoreit predicts the emergence of around 700 mRNA-based drugs, highlighting the potential impact of AI in revolutionizing drug discovery and development.

Inceptive has not only attracted attention for its innovative approach but also for the caliber of its backers, with prominent Silicon Valley venture capitalists like Andreessen Horowitz and Nvidia Corporation's NVentures showing their support. NVentures, in particular, has previously invested $50 million in another promising drug discovery company, Recursion Pharmaceuticals, showcasing a keen interest in leveraging AI for medical advancements.

The collaboration with Nvidia provides Inceptive not just with funding but also access to cutting-edge tools, which will undoubtedly accelerate the startup's research and development efforts. This partnership is indicative of the broader industry trend where big-tech is increasingly converging with pharmaceutical science to explore new frontiers in medicine.

Such ventures are reshaping the way venture capital is being allocated, with an evident shift towards innovative solutions at the intersection of technology and healthcare. Morgan Stanley's forecast of a $50 billion opportunity for AI in Big Pharma underscores the high expectations and the burgeoning interest in this space. Nevertheless, challenges remain, as illustrated by the difficulties faced by companies like London-based Benevolent AI, which had to downsize significantly after its principal drug candidate faltered.

Criticism also persists regarding the overhype of AI's capabilities, alongside cautionary notes from regulatory bodies such as the US Federal Drug Administration (FDA), which has yet to approve any AI-designed drug. Despite these hurdles, the enthusiasm for AI in biotech, especially in projects like Inceptive's, continues to grow, driven by the potential for breakthroughs in drug discovery and the overarching goal of enhancing human health through innovation.


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OPEN SIDE NAVIGATION MENU Subscribe Sign In MENU Financial Times Subscribe Sign In Artificial intelligenceAdd to myFT Former Google AI expert raises $100mn for biotech start-up Inceptive’s Jakob Uszkoreit, a pioneer of the technology behind ChatGPT, attracts Nvidia funding to design ‘biological software’

The latest round of funding for Jakob Uszkoreit’s start-up has more than tripled its most recent valuation of $100mn, people close to the deal said Former Google AI expert raises $100mn for biotech start-up on x (opens in a new window) Former Google AI expert raises $100mn for biotech start-up on facebook (opens in a new window) Former Google AI expert raises $100mn for biotech start-up on linkedin (opens in a new window) Save Madhumita Murgia in LondonSEPTEMBER 6 2023 50 Print this page Stay informed with free updates Simply sign up to the Artificial intelligence myFT Digest -- delivered directly to your inbox.

A biotech start-up founded by a former Google artificial intelligence expert has raised $100mn from Silicon Valley heavyweights Nvidia and Andreessen Horowitz as the market for generative AI applications expands into pharmaceuticals. 

Palo Alto-based Inceptive plans to use the funds to develop new types of vaccines and drugs. It is designing “biological software” using the latest AI technology that was pioneered by the company’s founder Jakob Uszkoreit, who co-authored a paper that kick-started generative AI advances such as ChatGPT. 

Software programs code executable instructions on a computer, he said. “We want to do that but with cells in your body.”

Inceptive is one of a new generation of start-ups which have collectively raised billions of dollars to apply AI to drug development. It is part of a race by Big Pharma and investors to capitalise on a $50bn market opportunity for AI in the sector, according to a Morgan Stanley report.

The two-year-old start-up was last valued at $100mn in 2021 after it raised seed funding of $20mn. The latest round, which includes new investors such as Obvious Ventures, more than triples Inceptive’s valuation, according to a source close to the deal.  

The company has built an AI software platform that designs entirely unique molecules made of mRNA, the biological unit that Pfizer and BioNTech used to make their Covid-19 vaccines. Once Inceptive tests these in its labs, it licenses the molecules out to pharmaceutical companies to assemble and put through clinical trials. 

Inceptive said it was working with a large European pharmaceutical company, which is experimenting with the start-up’s molecules to develop a new infectious disease vaccine. The success of mRNA against Covid-19 has yet to be replicated in other vaccines.

“We want to provide this as a horizontal capability to any entity developing mRNA and later RNA medicines,” Uszkoreit said. “There are currently about 310 programs in flight, somewhere between pre-clinical and clinical trials.”

He added that “conservative estimates” indicate more than 700 mRNA drugs will be in development by the end of the decade.

Other biotechs that have announced drugs discovered or developed using AI tools include Exscientia, Verge Genomics and Recursion Pharmaceuticals. However, most of the time and cost of the drug development process is in the clinical trials, rather than designing molecules.

Uszkoreit, who spent most of his career at Google working on AI research, has always been interested in the biological applications of machine learning. When he was at the US tech giant, he explored the use of AI to predict the structure of human proteins. His work on transformers ultimately led to breakthrough research by Google DeepMind, the London-based AI unit, which invented AlphaFold, an algorithm designed to predict the structure of almost every known protein.

“We want to maximise the positive impact of this type of work in AI,” he said.

Uszkoreit co-wrote the transformers research paper first published in June 2017. Since then, all of its co-authors have left Google, primarily to found their own start-ups as the race for generative AI talent heats up globally. 

Recommended

The Big Read Transformers: the Google scientists who pioneered an AI revolution

NVentures, Nvidia’s venture capital arm, is one of Inceptive’s new investors and has backed a number of AI-focused start-ups in recent months. They include Israeli AI21 Labs, which is building its own large language model to compete with the likes of Google and OpenAI, and Aleph Alpha, a German competitor to OpenAI.

Nvidia recently invested $50mn in another AI-powered drug discovery platform Recursion, based in Utah. Inceptive’s funding from NVentures is an equity investment but also gives it access to some of Nvidia’s most cutting-edge computing platforms, including its latest chips, the company said.

Nvidia declined to comment.

Additional reporting by Hannah Kuchler

This article has been amended to correct the age of Inceptive

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ME: Please extract the article

[AI]: A former Google artificial intelligence expert, Jakob Uszkoreit, has successfully raised $100 million for his biotech startup, Inceptive, with significant investments from Silicon Valley giants like Nvidia and Andreessen Horowitz. This considerable sum aims to bolster Inceptive's efforts in creating new types of vaccines and drugs through the development of "biological software." This innovative approach leverages the latest AI technology, a field in which Uszkoreit has been a pioneering figure, especially recognized for his contributions to generative AI advancements such as ChatGPT.

Located in Palo Alto, Inceptive is carving out a niche in the burgeoning intersection of AI and drug discovery, a sector predicted by Morgan Stanley to represent a $50 billion market opportunity. The startup's valuation has soared beyond its previous $100 million mark in 2021, thanks to this latest funding round.

Utilizing an AI software platform, Inceptive is crafting unique mRNA molecule designs. These designs are then tested in labs and potentially licensed out to pharmaceutical companies for further development and clinical trials. Inceptive's work includes a collaboration with a major European pharmaceutical company to develop a new vaccine for infectious diseases, highlighting the potential for mRNA technology outside its notable success in Covid-19 vaccines.

Inceptive is positioned in a rapidly expanding field where AI's potential to streamline the long and costly drug development process is increasingly recognized. Jakob Uszkoreit's background at Google, particularly his role in AI research and exploring the use of AI in predicting the structure of human proteins, has laid a foundational understanding that drives Inceptive's mission.

The investment by NVentures, Nvidia’s venture capital arm, not only provides Inceptive with equity but also access to Nvidia's state-of-the-art computing platforms and chips. This partnership underscores the tech industry's ongoing interest and investment in AI-driven biotech innovations, recognizing the transformative potential of combining cutting-edge computational power with biological research and development.


https://www.crunchbase.com/organization/inceptive-5b4a

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Search Crunchbase Search Crunchbase Inceptive Logo Inceptive Summary Financials People Technology Signals & News Similar Companies About Inceptive designs RNA molecules using large-scale deep learning in a tight loop with high-throughput experiments. Palo Alto, California, United States 11-50 Series A Private inceptive.life 1,435 Highlights Total Funding Amount Unlock for free Contacts 13 Employee Profiles 1 Investors 4 Similar Companies 15 Recent News & Activity News • Oct 30, 2023 Crunchbase News — How Former Googlers’ VC Firm Invests In Everything From LLMs To AI Doing Drug Discovery News • Oct 26, 2023 Crunchbase News — Andreessen Horowitz May Be Optimistic About Tech, But It’s Still Slowing Its Deal Pace News • Oct 11, 2023 Crunchbase News — Active Startup Investors Picked Up Their Pace Again In Q3 VIEW ALL Find More Contacts for Inceptive Engineer Non-Management Engineering 1 email found View contacts for Inceptive to access new leads and connect with decision-makers. Details Industries Biotechnology Life Science Medical Headquarters Regions San Francisco Bay Area, Silicon Valley, West Coast Founded Date 2021 Founders Jakob Uszkoreit, Rhiju Das Operating Status Active Last Funding Type Series A Also Known As Inceptive Nucleics Legal Name Inceptive Nucleics, Inc Company Type For Profit Contact Email info@inceptive.life Inceptive designs RNA molecules using large-scale deep learning in a tight loop with high-throughput experiments. They create tools to develop increasingly powerful biological software for the rational design of novel, broadly accessible medicines and biotechnologies previously out of reach. Lists Featuring This Company

California Life Science Companies

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Companies With Less Than $10M in Revenue (Top 10K) Frequently Asked Questions Where is Inceptive's headquarters? Inceptive is located in Palo Alto, California, United States. Who invested in Inceptive? Inceptive has 4 investors including Obvious Ventures and NVIDIA. How much funding has Inceptive raised to date? Inceptive has raised $120M. When was the last funding round for Inceptive? Inceptive closed its last funding round on Sep 7, 2023 from a Series A round. Who are Inceptive's competitors? Alternatives and possible competitors to Inceptive may include Eikon Therapeutics, Inceptive, and Vivodyne.

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ME: Please extract the article from this

[AI]: Inceptive is a pioneering company located in Palo Alto, California, at the forefront of biotechnology and life sciences. Founded in 2021 by Jakob Uszkoreit and Rhiju Das, Inceptive stands out for its innovative approach to drug discovery and biotechnology development. Through the design of RNA molecules, the company harnesses the power of large-scale deep learning in conjunction with high-throughput experiments. This highly sophisticated process aims at developing more advanced biological software, paving the way for the creation of novel medicines and biotechnologies that were previously considered out of reach.

Operating under the legal name Inceptive Nucleics, Inc., this privately held company has secured its position in the competitive biotech industry by closing its last funding round on September 7, 2023, through a Series A investment. To date, Inceptive has raised a total of $120 million. Its ability to attract significant investment is a testament to the promising potential of its technology and approach to medicine development. Inceptive counts among its investors notable names such as Obvious Ventures and NVIDIA, underscoring the company's strong foundation and the industry's belief in its groundbreaking work.

Inceptive is strategically headquartered in the San Francisco Bay Area, placing it at the heart of the Silicon Valley innovation hub. With a team of 11 to 50 employees, the company is part of a vibrant ecosystem of tech and biotech innovators. Inceptive is known also by another name, Inceptive Nucleics, emphasizing its core focus on RNA research and nucleic acid technologies.

The company's mission centers around the use of deep learning algorithms and rapid experimental techniques to create powerful tools for the rational design of new, universally accessible cures and biotechnologies. This mission reflects a broader trend in the biotech industry towards leveraging artificial intelligence and computational methods to solve complex biological problems.

Inceptive's influence extends beyond the laboratory and investment realms into the media, as highlighted by its appearance in various news articles throughout October 2023. These articles showcase the interest and optimism surrounding venture capital investments in companies that are innovating at the intersection of artificial intelligence and drug discovery, positioning Inceptive as a key player in this rapidly evolving field.

Comparative analysis suggests that Inceptive's innovative approach places it among a select group of companies such as Eikon Therapeutics and Vivodyne, which are also striving to revolutionize biotechnologies and medical treatments. The shared goal among these competitors is to harness the power of technology to unlock new possibilities in healthcare and medicine, making previously untreatable conditions manageable and even curable.

Inceptive's contact information is readily available for those interested in learning more about its revolutionary work. With the company's contact email listed as info@inceptive.life, potential collaborators, investors, and researchers can easily reach out to explore opportunities for partnership and innovation. As Inceptive continues to grow and evolve, it stands as a beacon of hope in the quest for more effective, accessible, and innovative healthcare solutions.